GENERAL SUMMARY/ OVERVIEW STATEMENT:

The Evavold Laboratory (https://ragoninstitute.org/evavold/) at the Ragon Institute of Mass General, MIT, and Harvard invites applications for a Lab Technician position. We seek a passionate, motivated individual that brings a positive outlook to research tasks and maintenance of lab operations. The Evavold Lab focuses on the basic decision making of cells towards different cell fates using cell death programs as a model system. Projects utilize genetic screening, synthetic biology, and mRNA technology development applied to host-pathogen interactions, vaccinology, and cancer immunology.

The candidate will assist in research aimed at defining molecular and cell biological regulation of cell death in the context of the innate immune system. These studies will combine techniques from molecular biology, cell biology, microbiology, immunology, and metabolism to probe cellular decision making. Recent studies have combined the use of synthetic biology to model signaling nodes within a canonical pathway under precise chemical control coupled to targeted or genome-wide genetic perturbations.

This position is ideal for candidates who are interested in pursuing a career in biomedical research, industry, or medicine. A commitment of at least 2 years by the candidate is of high priority to the lab to ensure adequate time for training and continuity of projects in the lab. The Ragon Institute serves as an ideal setting for this training and research opportunity with access to state-of-the-art facilities and technologies in a highly collaborative environment.

PRINCIPAL DUTIES AND RESPONSIBILITIES:

• Attends and participates in lab and institutional meetings
• Maintains an orderly laboratory notebook with detailed documentation
• Regular cataloguing and back-up of experimental data files
• Understands and applies basic scientific techniques (e.g. antibody staining, flow cytometry, DNA/RNA extraction and analysis, standard and quantitative PCR, ELISA, cloning)
• Cell/tissue processing, culture, and maintenance
• Independently performs routine and non-routine experiments that are moderate to complex
• Conducts analysis of results
• Prepares lab reagents, chemicals, instruments and equipment
• Performs independent literature searches
• Assists with organizing materials for publication or presentation
• Maintains and orders supplies

SKILLS/ABILITIES/COMPETENCIES REQUIRED:

• Self-motivation and strong organizational skills
• Prior experience in an immunology, microbiology, biochemistry, or molecular biology lab
• Familiarity with experimental biology techniques
• Open to occasional handling of laboratory mice
• Ability to work independently and as a team member
• Good communication skills
• Computer literacy
• Some occasional weekend or evening flexibility may be required

EDUCATION:

• Bachelor's degree required.
  

EXPERIENCE:

• New graduates with some lab experience (via course work, internships, etc.) or those without any prior research experience will be considered for the Research Technician I position outlined above.

Massachusetts General Hospital is an Affirmative Action Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.