Biologics Pilot Plant Process Operations Scientist / Upstream and Downstream
Lincoln, NE 
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Posted 25 days ago
Job Description

Role Description:

Zoetis is the largest animal health company in the world with an industry-leading veterinary medicine research and development team. We are seeking a talented and motivated bioprocess scientist / bioprocess engineer to join our research and development team to complete final development, scale-up and transfer of new vaccines into the pilot plant in support of new product registration.

As a scientist working in the pilot plant, the individual should have technical knowledge in at least one unit operation which may include bacterial fermentation, production of conventional viral antigens, purified proteins, vaccine formulation, and/or lyophilization. Working knowledge of fermenters, single use bioreactors, and associated downstream processing equipment from a 50L to 1000L scale and/or formulation experience with adjuvanted vaccines, emulsification processes and lyophization equipment at a 20 - 200L scale are highly desired.

The successful candidate will work with minimal supervision in a GMP-regulated environment in close collaboration with a range of scientists and manufacturing representatives across the organization. This job requires an independent thinker with demonstrated abilities to carry out assigned responsibilities and collaborate effectively with other team members.

The position is based in Lincoln (Nebraska, USA) with frequent interactions with colleagues and external partners located around the globe.

Employee Responsibilities:

  • Support pilot-scale campaigns for the GMP manufacture of biologic clinical supplies. This may include production of upstream growth, downstream processing, aseptic formulation and filling activities for (vaccines and therapeutic proteins).
  • Preparation, execution and close out of a GMP campaign, including campaign document preparation, determination and design of components, consumables and parts.
  • Hands-on participation in the execution of GMP batches for any of the following unit operations:
    • Aseptic inoculation and growth of cultures through various vessels types and systems.
    • Downstream purification unit operations such as cross-flow filtration, centrifugation, process chromatography, precipitation, ultrafiltration, and sterile filtration.
    • Formulation activities utilizing sterile solutions, emulsification equipment, automated filling lines, and lyophilization.
    • Supporting cleaning and steam-in-place activities for equipment.
  • Work in a multi-discipline project team environment, contribute at the technical level with project teams and provide information to support decision making in the realm of process scale up and transfer.

Organizational Relationships:

  • The position is located in the Pilot Lab within Biologics Process and Product Sciences.
  • The scientist will interact with peers and colleagues working in disciplines that include registration lab, pilot lab, cell line development, upstream development, downstream development, formulation development, quality operations, and regulatory affairs.
  • The position works in partnership with colleagues in Global Manufacturing Technologies to transfer developed processes to Global Manufacturing Supply for commercial production.
  • The individual is expected to form collaborative working relationships with project team leaders and line representatives within team settings.
  • The position may also interact with external parties including vendors, contractors, research collaborators, and contract manufacturers.

Education:

  • BS in Biological Sciences or BioSystems Engineering fields is required with a minimum of 1-3 years of relevant experience.

The Ideal candidate would possess:

  • Experience with working in a GMP environment.
  • Knowledge of GMP documentation requirements, ability to keep accurate records and comply with company policies.
  • Previous experience in upstream and/or downstream processing of bulk biological products (vaccines and purified proteins).
  • Excellent communication (written and oral) with attention to detail.
  • Self-starter, able to prioritize work on multiple concurrent programs and work efficiently with minimal supervision.
  • Strong computer, scientific, and organization skills.
  • Demonstrated record of working in a team environment.

Full time

Regular

Colleague

Any unsolicited resumes sent to Zoetis from a third party, such as an Agency recruiter, including unsolicited resumes sent to a Zoetis mailing address, fax machine or email address, directly to Zoetis employees, or to Zoetis resume database will be considered Zoetis property. Zoetis will NOT pay a fee for any placement resulting from the receipt of an unsolicited resume.

Zoetis will consider any candidate for whom an Agency has submitted an unsolicited resume to have been referred by the Agency free of any charges or fees. This includes any Agency that is an approved/engaged vendor but does not have the appropriate approvals to be engaged on a search.

Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability. Please contact Zoetis Colleague Services at zoetiscolleagueservices@zoetis.com to request an accommodation. Zoetis also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must possess or obtain authorization to work in the US for Zoetis. Zoetis retains sole and exclusive discretion to pursue sponsorship for the acquisition or maintenance of nonimmigrant status and employment eligibility, considering factors such as availability of qualified US workers. Individuals requiring sponsorship must disclose this fact. Please note that Zoetis seeks information related to job applications from candidates for jobs in the U.S. solely via the following: (1) our company website at www.Zoetis.com/careers site, or (2) via email to/from addresses using only the Zoetis domain of "@zoetis.com". In addition, Zoetis does not use Google Hangout for any recruitment related activities. Any solicitation or request for information related to job applications with Zoetis via any other means and/or utilizing email addresses with any other domain should be disregarded. In addition, Zoetis will never ask candidates to make any type of personal financial investment related to gaining employment with Zoetis.

 

Job Summary
Company
Start Date
As soon as possible
Employment Term and Type
Regular, Full Time
Required Experience
1 to 3 years
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